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Active Efflux of Ciprofloxacin from J774 Macrophages through an MRP-Like Transporter
The accumulation and efflux kinetics of ciprofloxacin have been examined by using murine J774 macrophages. Accumulation (at equilibrium) was increased (three- to fourfold) (i) when cells were incubated with high extracellular drug concentrations (typically 200 mg/liter) as opposed to clinically mean...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC434197/ https://ncbi.nlm.nih.gov/pubmed/15215125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.7.2673-2682.2004 |
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