Identification of the Efflux Transporter of the Fluoroquinolone Antibiotic Ciprofloxacin in Murine Macrophages: Studies with Ciprofloxacin-Resistant Cells

Ciprofloxacin, the most widely used totally synthetic antibiotic, is subject to active efflux mediated by a MRP-like transporter in wild-type murine J774 macrophages. To identify the transporter among the seven potential Mrps, we used cells made resistant to ciprofloxacin obtained by long-term expos...

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Detaylı Bibliyografya
Asıl Yazarlar: Marquez, Béatrice, Caceres, Nancy E., Mingeot-Leclercq, Marie-Paule, Tulkens, Paul M., Van Bambeke, Françoise
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2009
Konular:
Pharmacology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687251/
https://ncbi.nlm.nih.gov/pubmed/19307362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01428-08
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