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Active Efflux of Ciprofloxacin from J774 Macrophages through an MRP-Like Transporter

The accumulation and efflux kinetics of ciprofloxacin have been examined by using murine J774 macrophages. Accumulation (at equilibrium) was increased (three- to fourfold) (i) when cells were incubated with high extracellular drug concentrations (typically 200 mg/liter) as opposed to clinically mean...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Michot, Jean-Michel, Van Bambeke, Françoise, Mingeot-Leclercq, Marie-Paule, Tulkens, Paul M.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2004
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC434197/
https://ncbi.nlm.nih.gov/pubmed/15215125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.7.2673-2682.2004
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