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Comparing SILAC- and Stable Isotope Dimethyl-Labeling Approaches for Quantitative Proteomics

[Image: see text] Stable isotope labeling is widely used to encode and quantify proteins in mass-spectrometry-based proteomics. We compared metabolic labeling with stable isotope labeling by amino acids in cell culture (SILAC) and chemical labeling by stable isotope dimethyl labeling and find that t...

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Bibliografiske detaljer
Main Authors: Lau, Ho-Tak, Suh, Hyong Won, Golkowski, Martin, Ong, Shao-En
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2014
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156256/
https://ncbi.nlm.nih.gov/pubmed/25077673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr500630a
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