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Quantitative Proteomics Using Reductive Dimethylation for Stable Isotope Labeling

Stable isotope labeling of peptides by reductive dimethylation (ReDi labeling) is a method to accurately quantify protein expression differences between samples using mass spectrometry. ReDi labeling is performed using either regular (light) or deuterated (heavy) forms of formaldehyde and sodium cya...

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Detalhes bibliográficos
Main Authors: Tolonen, Andrew C., Haas, Wilhelm
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210151/
https://ncbi.nlm.nih.gov/pubmed/25045933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/51416
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