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Illegitimate recombination induced by DNA double-strand breaks in a mammalian chromosome.

We examined DNA double-strand-break-induced mutations in the endogenous adenine phosphoribosyl-transferase (APRT) gene in cultured Chinese hamster ovary cells after exposure to restriction endonucleases. PvuII, EcoRV, and StuI, all of which produce blunt-end DNA double-strand breaks, were electropor...

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Detaylı Bibliyografya
Asıl Yazarlar: Phillips, J W, Morgan, W F
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1994
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC359105/
https://ncbi.nlm.nih.gov/pubmed/8065314
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