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Illegitimate recombination induced by DNA double-strand breaks in a mammalian chromosome.
We examined DNA double-strand-break-induced mutations in the endogenous adenine phosphoribosyl-transferase (APRT) gene in cultured Chinese hamster ovary cells after exposure to restriction endonucleases. PvuII, EcoRV, and StuI, all of which produce blunt-end DNA double-strand breaks, were electropor...
Guardat en:
| Publicat a: | Mol Cell Biol |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
1994
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359105/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8065314/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.9.5794 |
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