Illegitimate recombination induced by DNA double-strand breaks in a mammalian chromosome.

We examined DNA double-strand-break-induced mutations in the endogenous adenine phosphoribosyl-transferase (APRT) gene in cultured Chinese hamster ovary cells after exposure to restriction endonucleases. PvuII, EcoRV, and StuI, all of which produce blunt-end DNA double-strand breaks, were electropor...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Phillips, J W, Morgan, W F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359105/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8065314/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.9.5794-5803.1994
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