Illegitimate recombination induced by DNA double-strand breaks in a mammalian chromosome.

We examined DNA double-strand-break-induced mutations in the endogenous adenine phosphoribosyl-transferase (APRT) gene in cultured Chinese hamster ovary cells after exposure to restriction endonucleases. PvuII, EcoRV, and StuI, all of which produce blunt-end DNA double-strand breaks, were electropor...

Full description

Bibliographic Details

Published in:	Mol Cell Biol
Main Authors:	Phillips, J W, Morgan, W F
Format:	Artigo
Language:	Inglês
Published:	Taylor & Francis 1994
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359105/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8065314/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.9.5794-5803.1994
Tags:	Add Tag No Tags, Be the first to tag this record!