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Transforming growth factor alpha dramatically enhances oncogene-induced carcinogenesis in transgenic mouse pancreas and liver.

To characterize the effect(s) of transforming growth factor alpha (TGF alpha) during multistage carcinogenesis, we examined tumor development in pancreas and liver of transgenic mice that coexpressed TGF alpha with either viral (simian virus 40 T antigens [TAg]) or cellular (c-myc) oncogenes. In pan...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Sandgren, E P, Luetteke, N C, Qiu, T H, Palmiter, R D, Brinster, R L, Lee, D C
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1993
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358911/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8417334/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.1.320-330.1993
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