Transforming growth factor alpha dramatically enhances oncogene-induced carcinogenesis in transgenic mouse pancreas and liver.

To characterize the effect(s) of transforming growth factor alpha (TGF alpha) during multistage carcinogenesis, we examined tumor development in pancreas and liver of transgenic mice that coexpressed TGF alpha with either viral (simian virus 40 T antigens [TAg]) or cellular (c-myc) oncogenes. In pan...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Sandgren, E P, Luetteke, N C, Qiu, T H, Palmiter, R D, Brinster, R L, Lee, D C
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358911/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8417334/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.1.320-330.1993
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