Transforming growth factor alpha dramatically enhances oncogene-induced carcinogenesis in transgenic mouse pancreas and liver.

To characterize the effect(s) of transforming growth factor alpha (TGF alpha) during multistage carcinogenesis, we examined tumor development in pancreas and liver of transgenic mice that coexpressed TGF alpha with either viral (simian virus 40 T antigens [TAg]) or cellular (c-myc) oncogenes. In pan...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Sandgren, E P, Luetteke, N C, Qiu, T H, Palmiter, R D, Brinster, R L, Lee, D C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358911/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8417334/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.1.320-330.1993
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