Caspase-1 deficiency in mice reduces intestinal triglyceride absorption and hepatic triglyceride secretion

Caspase-1 is known to activate the proinflammatory cytokines IL-1β and IL-18. Additionally, it can cleave other substrates, including proteins involved in metabolism. Recently, we showed that caspase-1 deficiency in mice strongly reduces high-fat diet-induced weight gain, at least partly caused by a...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: van Diepen, Janna A., Stienstra, Rinke, Vroegrijk, Irene O. C. M., van den Berg, Sjoerd A. A., Salvatori, Daniela, Hooiveld, Guido J., Kersten, Sander, Tack, Cees J., Netea, Mihai G., Smit, Johannes W.A., Joosten, Leo A. B., Havekes, Louis M., van Dijk, Ko Willems, Rensen, Patrick C. N.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The American Society for Biochemistry and Molecular Biology 2013
Θέματα:
Research Articles
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3588871/
https://ncbi.nlm.nih.gov/pubmed/23160218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M031963
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