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Caspase-1 deficiency in mice reduces intestinal triglyceride absorption and hepatic triglyceride secretion
Caspase-1 is known to activate the proinflammatory cytokines IL-1β and IL-18. Additionally, it can cleave other substrates, including proteins involved in metabolism. Recently, we showed that caspase-1 deficiency in mice strongly reduces high-fat diet-induced weight gain, at least partly caused by a...
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| Główni autorzy: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The American Society for Biochemistry and Molecular Biology
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3588871/ https://ncbi.nlm.nih.gov/pubmed/23160218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M031963 |
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