Inhibition of the prostaglandin receptor EP2 following status epilepticus reduces delayed mortality and brain inflammation

Prostaglandin E2 is now widely recognized to play critical roles in brain inflammation and injury, although the responsible prostaglandin receptors have not been fully identified. We developed a potent and selective antagonist for the prostaglandin E2 receptor subtype EP2, TG6-10-1, with a sufficien...

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Bibliographische Detailangaben
Hauptverfasser: Jiang, Jianxiong, Quan, Yi, Ganesh, Thota, Pouliot, Wendy A., Dudek, F. Edward, Dingledine, Raymond
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587237/
https://ncbi.nlm.nih.gov/pubmed/23401547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218498110
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