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Therapeutic window for cyclooxygenase-2 related anti-inflammatory therapy after status epilepticus
As a prominent inflammatory effector of cyclooxygenase-2 (COX-2), prostaglandin E2 (PGE(2)) mediates brain inflammation and injury in many chronic central nervous system (CNS) conditions including seizures and epilepsy, largely through its receptor subtype EP2. However, EP2 receptor activation might...
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Publicado no: | Neurobiol Dis |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4408774/ https://ncbi.nlm.nih.gov/pubmed/25600211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.12.032 |
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