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Therapeutic window for cyclooxygenase-2 related anti-inflammatory therapy after status epilepticus

As a prominent inflammatory effector of cyclooxygenase-2 (COX-2), prostaglandin E2 (PGE(2)) mediates brain inflammation and injury in many chronic central nervous system (CNS) conditions including seizures and epilepsy, largely through its receptor subtype EP2. However, EP2 receptor activation might...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Jiang, Jianxiong, Yang, Myung-Soon, Quan, Yi, Gueorguieva, Paoula, Ganesh, Thota, Dingledine, Raymond
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408774/
https://ncbi.nlm.nih.gov/pubmed/25600211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.12.032
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