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Therapeutic window for cyclooxygenase-2 related anti-inflammatory therapy after status epilepticus

As a prominent inflammatory effector of cyclooxygenase-2 (COX-2), prostaglandin E2 (PGE(2)) mediates brain inflammation and injury in many chronic central nervous system (CNS) conditions including seizures and epilepsy, largely through its receptor subtype EP2. However, EP2 receptor activation might...

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Vydáno v:Neurobiol Dis
Hlavní autoři: Jiang, Jianxiong, Yang, Myung-Soon, Quan, Yi, Gueorguieva, Paoula, Ganesh, Thota, Dingledine, Raymond
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408774/
https://ncbi.nlm.nih.gov/pubmed/25600211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.12.032
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