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Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy
Autophagy is a stress response protecting cells from unfavorable conditions, such as nutrient starvation. The class III phosphatidylinositol-3 kinase, Vps34, forms multiple complexes and regulates both intracellular vesicle trafficking and autophagy induction. Here, we show that AMPK plays a key rol...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3587159/ https://ncbi.nlm.nih.gov/pubmed/23332761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.12.016 |
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