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Regulation of PIK3C3/VPS34 complexes by MTOR in nutrient stress-induced autophagy

Autophagy is a cellular defense response to stress conditions, such as nutrient starvation. The type III phosphatidylinositol (PtdIns) 3-kinase, whose catalytic subunit is PIK3C3/VPS34, plays a critical role in intracellular membrane trafficking and autophagy induction. PIK3C3 forms multiple complex...

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Detalhes bibliográficos
Main Authors: Yuan, Hai-Xin, Russell, Ryan C, Guan, Kun-Liang
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028342/
https://ncbi.nlm.nih.gov/pubmed/24013218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.26058
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