Autophagy-related protein PIK3C3/VPS34 controls T cell metabolism and function: PIK3C3/VPS34 in T cell metabolism and function

The PIK3C3/VPS34 subunit of the class III phosphatidylinositol 3-kinase (PtdIns3K) complex is a key early player in macroautophagy/autophagy. In this study, we assessed the contribution of PIK3C3 to T cell metabolism and function. We found that Pik3c3-deficient T cells exhibited impaired cellular me...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Yang, Guan, Song, Wenqiang, Postoak, J. Luke, Chen, Jin, Martinez, Jennifer, Zhang, Jianhua, Wu, Lan, Van Kaer, Luc
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8143264/
https://ncbi.nlm.nih.gov/pubmed/32268825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1752979
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