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Effects of neuronal PIK3C3/Vps34 deletion on autophagy and beyond

PIK3C3/Vps34 plays important roles in the endocytic and autophagic pathways, both of which are essential for maintaining neuronal integrity. However, it is unclear how inactivating PIK3C3 may affect neuronal endosomal versus autophagic processes in vivo. We generated a conditional null allele of the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhou, Xiang, Wang, Fan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321846/
https://ncbi.nlm.nih.gov/pubmed/20562532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.6.6.12511
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