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Effects of neuronal PIK3C3/Vps34 deletion on autophagy and beyond

PIK3C3/Vps34 plays important roles in the endocytic and autophagic pathways, both of which are essential for maintaining neuronal integrity. However, it is unclear how inactivating PIK3C3 may affect neuronal endosomal versus autophagic processes in vivo. We generated a conditional null allele of the...

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Detalles Bibliográficos
Main Authors: Zhou, Xiang, Wang, Fan
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321846/
https://ncbi.nlm.nih.gov/pubmed/20562532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.6.6.12511
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