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Unsaturation, curvature and charge: effects of membrane parameters on PIK3C3/VPS34-containing complexes

Phosphatidylinositol-3-phosphate (PtdIns3P) is essential for generating autophagosomes and regulating endocytic trafficking. Recently, we have shown that the activities of human PIK3C3/VPS34-containing complexes I and II, which synthesize PtdIns3P, are greatly affected by three membrane physicochemi...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Ohashi, Yohei, Tremel, Shirley, Williams, Roger L.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8032224/
https://ncbi.nlm.nih.gov/pubmed/33446010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2021.1872190
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