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Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy

Autophagy is a stress response protecting cells from unfavorable conditions, such as nutrient starvation. The class III phosphatidylinositol-3 kinase, Vps34, forms multiple complexes and regulates both intracellular vesicle trafficking and autophagy induction. Here, we show that AMPK plays a key rol...

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Detalhes bibliográficos
Main Authors: Kim, Joungmok, Kim, Young Chul, Fang, Chong, Russell, Ryan C., Kim, Jeong Hee, Fan, Weiliang, Liu, Rong, Zhong, Qing, Guan, Kun-Liang
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587159/
https://ncbi.nlm.nih.gov/pubmed/23332761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.12.016
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