Cav1 Suppresses Tumor Growth and Metastasis in a Murine Model of Cutaneous SCC through Modulation of MAPK/AP-1 Activation

Caveolin-1 (Cav1) is a scaffolding protein that serves to regulate the activity of several signaling molecules. Its loss has been implicated in the pathogenesis of several types of cancer, but its role in the development and progression of cutaneous squamous cell carcinoma (cSCC) remains largely une...

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Bibliographische Detailangaben
Hauptverfasser: Trimmer, Casey, Bonuccelli, Gloria, Katiyar, Sanjay, Sotgia, Federica, Pestell, Richard G., Lisanti, Michael P., Capozza, Franco
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2013
Schlagworte:
Regular Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586688/
https://ncbi.nlm.nih.gov/pubmed/23267770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.11.008
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