Genetic ablation of Cav1 differentially affects melanoma tumor growth and metastasis in mice. Role of Cav1 in Shh heterotypic signaling and transendothelial migration

Both cell-autonomous and non-cell-autonomous factors contribute to tumor growth and metastasis of melanoma. The function of Caveolin-1 (Cav1), a multifunctional scaffold protein known to modulate several biological processes in both normal tissue and cancer, has been recently investigated in melanom...

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Detalhes bibliográficos
Main Authors: Capozza, Franco, Trimmer, Casey, Castello-Cros, Remedios, Katiyar, Sanjay, Whitaker-Menezes, Diana, Follenzi, Antonia, Crosariol, Marco, Llaverias, Gemma, Sotgia, Federica, Pestell, Richard G, Lisanti, Michael P
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342428/
https://ncbi.nlm.nih.gov/pubmed/22396494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2593
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