CAV1 Inhibits Metastatic Potential in Melanomas through Suppression of the Integrin/Src/FAK Signaling Pathway

Caveolin-1 (CAV1) is the main structural component of Caveolae which are plasma membrane invaginations that participate in vesicular trafficking and signal transduction events. Although evidence has recently accumulated describing the function of CAV1 in several cancer types, its role in melanoma tu...

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Main Authors: Trimmer, Casey, Whitaker-Menezes, Diana, Bonuccelli, Gloria, Milliman, Janet N, Daumer, Kristin M, Aplin, Andrew E, Pestell, Richard G, Sotgia, Federica, Lisanti, Michael P, Capozza, Franco
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948597/
https://ncbi.nlm.nih.gov/pubmed/20709760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0900
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