Caveolin-1((−/−))- and Caveolin-2((−/−))-Deficient Mice Both Display Numerous Skeletal Muscle Abnormalities, with Tubular Aggregate Formation

Here, we examine the role of “non-muscle” caveolins (Cav-1 and Cav-2) in skeletal muscle biology. Our results indicate that skeletal muscle fibers from male Cav-1((−/−)) and Cav-2((−/−)) mice show striking abnormalities, such as tubular aggregates, mitochondrial proliferation/aggregation, and increa...

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Detalhes bibliográficos
Main Authors: Schubert, William, Sotgia, Federica, Cohen, Alex W., Capozza, Franco, Bonuccelli, Gloria, Bruno, Claudio, Minetti, Carlo, Bonilla, Eduardo, DiMauro, Salvatore, Lisanti, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762679/
https://ncbi.nlm.nih.gov/pubmed/17200204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060687
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