Polymeric nanoparticle PET/MR imaging allows macrophage detection in atherosclerotic plaques

RATIONALE: Myeloid cell content in atherosclerotic plaques associates with rupture and thrombosis. Thus, imaging of lesional monocyte and macrophages (Mo/Mϕ) could serve as a biomarker of disease progression and therapeutic intervention. OBJECTIVE: To noninvasively assess plaque inflammation with de...

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Detalhes bibliográficos
Main Authors: Majmudar, Maulik D., Yoo, Jeongsoo, Keliher, Edmund J., Truelove, Jessica, Iwamoto, Yoshiko, Sena, Brena, Dutta, Partha, Borodovsky, Anna, Fitzgerald, Kevin, Di Carli, Marcelo, Libby, Peter, Anderson, Daniel G., Swirski, Filip K., Weissleder, Ralph, Nahrendorf, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586287/
https://ncbi.nlm.nih.gov/pubmed/23300273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.111.300576
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