E-selectin inhibition mitigates splenic HSC activation and myelopoiesis in hypercholesterolemic mice with myocardial infarction

OBJECTIVE: Atherosclerosis is a chronic disease characterized by lipid accumulation in the arterial wall. After MI, atherosclerotic plaques are infiltrated by inflammatory myeloid cells that aggravate the disease and increase the risk of secondary myocardial ischemia. Splenic myelopoiesis provides a...

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Bibliografiska uppgifter
I publikationen:Arterioscler Thromb Vasc Biol
Huvudupphovsmän: Dutta, Partha, Hoyer, Friedrich Felix, Sun, Yuan, Iwamoto, Yoshiko, Tricot, Benoit, Weissleder, Ralph, Magnani, John L., Swirski, Filip K., Nahrendorf, Matthias
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001901/
https://ncbi.nlm.nih.gov/pubmed/27470513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.307519
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