E-selectin inhibition mitigates splenic HSC activation and myelopoiesis in hypercholesterolemic mice with myocardial infarction

OBJECTIVE: Atherosclerosis is a chronic disease characterized by lipid accumulation in the arterial wall. After MI, atherosclerotic plaques are infiltrated by inflammatory myeloid cells that aggravate the disease and increase the risk of secondary myocardial ischemia. Splenic myelopoiesis provides a...

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Bibliografiske detaljer
Udgivet i:Arterioscler Thromb Vasc Biol
Main Authors: Dutta, Partha, Hoyer, Friedrich Felix, Sun, Yuan, Iwamoto, Yoshiko, Tricot, Benoit, Weissleder, Ralph, Magnani, John L., Swirski, Filip K., Nahrendorf, Matthias
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001901/
https://ncbi.nlm.nih.gov/pubmed/27470513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.307519
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