Tumor Microsatellite-Instability Status as a Predictor of Benefit from Fluorouracil-Based Adjuvant Chemotherapy for Colon Cancer

BACKGROUND: Colon cancers with high-frequency microsatellite instability have clinical and pathological features that distinguish them from microsatellite-stable tumors. We investigated the usefulness of microsatellite-instability status as a predictor of the benefit of adjuvant chemotherapy with fl...

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Autori principali: Ribic, Christine M., Sargent, Daniel J., Moore, Malcolm J., Thibodeau, Stephen N., French, Amy J., Goldberg, Richard M., Hamilton, Stanley R., Laurent-Puig, Pierre, Gryfe, Robert, Shepherd, Lois E., Tu, Dongsheng, Redston, Mark, Gallinger, Steven
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2003
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584639/
https://ncbi.nlm.nih.gov/pubmed/12867608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa022289
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