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Targeting lysophosphatidic acid receptor type 1 with Debio 0719 inhibits spontaneous metastasis dissemination of breast cancer cells independently of cell proliferation and angiogenesis

Metastasis is the main cause of death for cancer patients. Targeting factors that control metastasis formation is a major challenge for clinicians. Lysophosphatidic acid (LPA) is a bioactive phospholipid involved in cancer. LPA activates at least six independent G protein-coupled receptors (LPA(1–6)...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: DAVID, MARION, RIBEIRO, JOHNNY, DESCOTES, FRANÇOISE, SERRE, CLAIRE-MARIE, BARBIER, MARYSE, MURONE, MAXIMILIEN, CLÉZARDIN, PHILIPPE, PEYRUCHAUD, OLIVIER
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: D.A. Spandidos 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584523/
https://ncbi.nlm.nih.gov/pubmed/22200658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2011.1309
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