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Platelet-derived lysophosphatidic acid supports the progression of osteolytic bone metastases in breast cancer
The role of lysophosphatidic acid (LPA) in cancer is poorly understood. Here we provide evidence for a role of LPA in the progression of breast cancer bone metastases. LPA receptors LPA(1), LPA(2), and LPA(3) were expressed in human primary breast tumors and a series of human breast cancer cell line...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2004
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC535068/ https://ncbi.nlm.nih.gov/pubmed/15599396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200422123 |
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