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Platelet-derived lysophosphatidic acid supports the progression of osteolytic bone metastases in breast cancer

The role of lysophosphatidic acid (LPA) in cancer is poorly understood. Here we provide evidence for a role of LPA in the progression of breast cancer bone metastases. LPA receptors LPA(1), LPA(2), and LPA(3) were expressed in human primary breast tumors and a series of human breast cancer cell line...

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Detalhes bibliográficos
Main Authors: Boucharaba, Ahmed, Serre, Claire-Marie, Grès, Sandra, Saulnier-Blache, Jean Sébastien, Bordet, Jean-Claude, Guglielmi, Julien, Clézardin, Philippe, Peyruchaud, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC535068/
https://ncbi.nlm.nih.gov/pubmed/15599396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200422123
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