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The type 1 lysophosphatidic acid receptor is a target for therapy in bone metastases
Platelet-derived lysophosphatidic acid (LPA) supports the progression of breast and ovarian cancer metastasis to bone. The mechanisms through which LPA promotes bone metastasis formation are, however, unknown. Here we report that silencing of the type 1 LPA receptor (LPA(1)) in cancer cells blocks t...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1480460/ https://ncbi.nlm.nih.gov/pubmed/16769891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600979103 |
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