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Perspective: pre-chemistry conformational changes in DNA polymerase mechanisms

In recent papers, there has been a lively exchange concerning theories for enzyme catalysis, especially the role of protein dynamics/pre-chemistry conformational changes in the catalytic cycle of enzymes. Of particular interest is the notion that substrate-induced conformational changes that assembl...

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Bibliografiske detaljer
Main Authors: Schlick, Tamar, Arora, Karunesh, Beard, William A., Wilson, Samuel H.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583561/
https://ncbi.nlm.nih.gov/pubmed/23459563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00214-012-1287-7
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