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Optimal and Variant Metal-Ion Routes in DNA Polymerase β’s Conformational Pathways
To interpret recent structures of the R283K mutant of human DNA repair enzyme DNA polymerase β (pol β) differing in the number of Mg(2+) ions, we apply transition path sampling (TPS) to assess the effect of differing ion placement on the transition from the open one-metal to the closed two-metal sta...
Tallennettuna:
| Julkaisussa: | J Am Chem Soc |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7032070/ https://ncbi.nlm.nih.gov/pubmed/24511902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja412701f |
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