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Revealing the role of the product metal in DNA polymerase β catalysis
DNA polymerases catalyze a metal-dependent nucleotidyl transferase reaction during extension of a DNA strand using the complementary strand as a template. The reaction has long been considered to require two magnesium ions. Recently, a third active site magnesium ion was identified in some DNA polym...
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| Publié dans: | Nucleic Acids Res |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5389463/ https://ncbi.nlm.nih.gov/pubmed/28108654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1363 |
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