Transitions in DNA polymerase β μs-ms dynamics related to substrate binding and catalysis

DNA polymerase β (pol β) plays a central role in the DNA base excision repair pathway and also serves as an important model polymerase. Dynamic characterization of pol β from methyl-TROSY (13)C-(1)H multiple quantum CPMG relaxation dispersion experiments of Ile and Met sidechains and previous backbo...

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Bibliografiska uppgifter
I publikationen:Nucleic Acids Res
Huvudupphovsmän: DeRose, Eugene F, Kirby, Thomas W, Mueller, Geoffrey A, Beard, William A, Wilson, Samuel H, London, Robert E
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2018
Ämnen:
Nucleic Acid Enzymes
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101544/
https://ncbi.nlm.nih.gov/pubmed/29917149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky503
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