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Substrate Rescue of DNA Polymerase β Containing a Catastrophic L22P Mutation
[Image: see text] DNA polymerase (pol) β is a multidomain enzyme with two enzymatic activities that plays a central role in the overlapping base excision repair and single-strand break repair pathways. The high frequency of pol β variants identified in tumor-derived tissues suggests a possible role...
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| Autors principals: | , , , , , |
|---|---|
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American
Chemical Society
2014
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4004254/ https://ncbi.nlm.nih.gov/pubmed/24655288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi5001855 |
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