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In Silico Evidence for DNA Polymerase-β's Substrate-Induced Conformational Change

Structural information for mammalian DNA pol-β combined with molecular and essential dynamics studies have provided atomistically detailed views of functionally important conformational rearrangements that occur during DNA repair and replication. This conformational closing before the chemical react...

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Autori principali: Arora, Karunesh, Schlick, Tamar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Biophysical Society 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304780/
https://ncbi.nlm.nih.gov/pubmed/15507687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.040915
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