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Regulation of DNA Repair Fidelity by Molecular Checkpoints: “Gates” in DNA Polymerase β’s Substrate Selection

With an increasing number of structural, kinetic, and modeling studies of diverse DNA polymerases in various contexts, a complex dynamical view of how atomic motions might define molecular “gates” or checkpoints that contribute to polymerase specificity and efficiency is emerging. Such atomic-level...

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Detalhes bibliográficos
Main Authors: Radhakrishnan, Ravi, Arora, Karunesh, Wang, Yanli, Beard, William A., Wilson, Samuel H., Schlick, Tamar
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1945116/
https://ncbi.nlm.nih.gov/pubmed/17176036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi061353z
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