A Cell-Delivered and –Activated SN38-Dextran Prodrug Increases Survival in a Murine Disseminated Pancreatic Cancer Model

Enzyme activated prodrugs have been investigated and sought after as highly specific, low side effect treatments, especially for cancer therapy. Unfortunately, excellent targets for enzyme activated therapy are rare. Here we demonstrate a system based on cell delivery that can carry both a prodrug a...

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Détails bibliographiques
Auteurs principaux: Basel, Matthew T., Balivada, Sivasai, Shrestha, Tej B., Seo, Gwi-Moon, Pyle, Marla M., Tamura, Masaaki, Bossmann, Stefan H., Troyer, Deryl L.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583224/
https://ncbi.nlm.nih.gov/pubmed/22238072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/smll.201101879
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