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A self-contained enzyme activating prodrug cytotherapy for preclinical melanoma
Gene-directed enzyme prodrug therapy (GDEPT) has been investigated as a means of cancer treatment without affecting normal tissues. This system is based on the delivery of a suicide gene, a gene encoding an enzyme which is able to convert its substrate from non-toxic prodrug to cytotoxin. In this ex...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3222711/ https://ncbi.nlm.nih.gov/pubmed/21567204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11033-011-0720-7 |
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