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Endoglin Deficiency in Bone Marrow Is Sufficient to Cause Cerebrovascular Dysplasia in the Adult Mouse after VEGF Stimulation
BACKGROUND AND PURPOSE: Bone marrow-derived cells (BMDCs) home to vascular endothelial growth factor (VEGF)-induced brain angiogenic foci, and VEGF induces cerebrovascular dysplasia in adult endoglin heterozygous (Eng(+/−)) mice. We hypothesized that Eng(+/−) BMDCs cause cerebrovascular dysplasia in...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3582755/ https://ncbi.nlm.nih.gov/pubmed/23306322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.112.671974 |
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