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Reduced mural cell coverage and impaired vessel integrity after angiogenic stimulation in the Alk1-deficient brain
OBJECTIVE: Vessels in brain arteriovenous malformations (bAVM) are prone to rupture. The underlying pathogenesis is not clear. Hereditary hemorrhagic telangiectasia type 2 (HHT2) patients with activin receptor-like kinase 1 (Alk1) mutation have a higher incidence of bAVM than the general population....
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| Main Authors: | , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3569037/ https://ncbi.nlm.nih.gov/pubmed/23241407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.300485 |
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