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De novo cerebrovascular malformation in the adult mouse after endothelial Alk1 deletion and angiogenic stimulation
BACKGROUND AND PURPOSE: In humans, activin receptor-like kinase 1 (Alk1) deficiency causes arteriovenous malformations (AVMs) in multiple organs, including the brain. Focal Alk1 pan-cellular deletion plus vascular endothelial growth factor (VEGF) stimulation induces brain AVMs (bAVMs) in the adult m...
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| Autores principales: | , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4117234/ https://ncbi.nlm.nih.gov/pubmed/24457293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.113.003655 |
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