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Bevacizumab attenuates VEGF-induced angiogenesis and vascular malformations in the adult mouse brain
BACKGROUND AND PURPOSE: Vascular endothelial growth factor (VEGF) expression is elevated in human brain arteriovenous malformations (bAVM). We have developed a bAVM model in the adult mouse by focal Alk1 gene deletion and human VEGF stimulation. We hypothesized that once the abnormal vasculature has...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3404823/ https://ncbi.nlm.nih.gov/pubmed/22569934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.111.647982 |
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