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Coexpression of angiopoietin-1 with VEGF increases the structural integrity of the blood–brain barrier and reduces atrophy volume

Vascular endothelial growth factor (VEGF)-induced neovasculature is immature and leaky. We tested if coexpression of angiopoietin-1 (ANG1) with VEGF improves blood–brain barrier (BBB) integrity and VEGF neuroprotective and neurorestorative effects using a permanent distal middle cerebral artery occl...

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Bibliografski detalji
Glavni autori: Shen, Fanxia, Walker, Espen J, Jiang, Lidan, Degos, Vincent, Li, Jianping, Sun, Baoliang, Heriyanto, Fransisca, Young, William L, Su, Hua
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323197/
https://ncbi.nlm.nih.gov/pubmed/21772310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.97
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