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Minimal Homozygous Endothelial Deletion of Eng with VEGF Stimulation is Sufficient to Cause Cerebrovascular Dysplasia in the Adult Mouse

BACKGROUND: Brain arteriovenous malformations (bAVMs) represent a high risk for hemorrhagic stroke, leading to significant neurological morbidity and mortality in young adults. The etiopathogenesis of bAVM remains unclear. Research progress has been hampered by the lack of animal models. Hereditary...

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Библиографические подробности
Главные авторы: Choi, Eun-Jung, Walker, Espen J., Shen, Fanxia, Oh, S. Paul, Arthur, Helen M., Young, William L., Su, Hua
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569027/
https://ncbi.nlm.nih.gov/pubmed/22571958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000337762
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