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Minimal Homozygous Endothelial Deletion of Eng with VEGF Stimulation is Sufficient to Cause Cerebrovascular Dysplasia in the Adult Mouse

BACKGROUND: Brain arteriovenous malformations (bAVMs) represent a high risk for hemorrhagic stroke, leading to significant neurological morbidity and mortality in young adults. The etiopathogenesis of bAVM remains unclear. Research progress has been hampered by the lack of animal models. Hereditary...

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Detalhes bibliográficos
Main Authors: Choi, Eun-Jung, Walker, Espen J., Shen, Fanxia, Oh, S. Paul, Arthur, Helen M., Young, William L., Su, Hua
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569027/
https://ncbi.nlm.nih.gov/pubmed/22571958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000337762
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