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The Relative Orientation of the TM3 and TM4 Domains Varies between α1 and α3 Glycine Receptors

[Image: see text] Glycine receptors (GlyRs) are anion-conducting members of the pentameric ligand-gated ion channel family. We previously showed that the dramatic difference in glycine efficacies of α1 and α3 GlyRs is largely attributable to their nonconserved TM4 domains. Because mutation of indivi...

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Detalhes bibliográficos
Main Authors: Han, Lu, Talwar, Sahil, Lynch, Joseph W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2012
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582286/
https://ncbi.nlm.nih.gov/pubmed/23421675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn300177g
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